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Adalimumab significantly reduces inflammation and serum DKK-1 level but increases fatty deposition in lumbar spine in active ankylosing spondylitis.

Hu, Zaiying   •   Xu, Manlong   •   Li, Qiuxia   •   Lin, Zhiming   •   Liao, Zetao   •   Cao, Shuangyan   •   Wei, Qiujing   •   Zhang, Yan Li   •   Li, Tianwang   •   Jin, Ou   •   Huang, Jianlin   •   Pan, Yunfeng   •   Wu, Yuqiong   •   Deng, Xinghe   •   Gu, Jieruo

published in: International journal of rheumatic diseases



endpoint

Adalimumab has (optional: compared with placebo) proved to be better.


basics

diagnosis:
ankylosing spondylitis

localization:
not specified

method:
conservative therapy → injection therapy
conservative therapy → injection

publication details

10.1111/j.1756-185X.2012.01734.x
pubmed
22898215
2012
Journal Article
randomized controlled trial
no
prospective
1+

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